Enzyme Production

Mammary gland bioreactor technology has emerged as a powerful platform for enzyme production, utilizing the natural protein-synthesizing and secreting capabilities of mammary glands in transgenic animals. This method enables large-scale production of recombinant enzymes, offering high yields at reduced costs while maintaining the structural integrity and bioactivity of the enzymes.

Types of Enzymes

The mammary gland bioreactor platform is capable of producing a wide range of enzymes tailored to specific applications.

Therapeutic Enzyme

Therapeutic enzymes are critical in treating various medical conditions by catalyzing biochemical reactions that replace or supplement deficient enzymes in patients.

DNase I: Used to treat cystic fibrosis by breaking down DNA in mucus, improving lung function.
Asparaginase: Applied in leukemia treatment to break down asparagine, starving cancer cells.
Uricase: Effective in treating gout by breaking down uric acid, reducing its levels in the body.

Industrial Enzyme

Industrial enzymes facilitate numerous processes across different sectors, including food production, textiles, biofuels, and detergents.

Proteases: Used in the food industry for protein hydrolysis and in detergents for stain removal.
Cellulases: Applied in biofuel production to break down cellulose into sugars, supporting ethanol production.
Lipases: Widely used in the dairy industry for flavor development in cheeses.

Nutritional Enzyme

Nutritional enzymes aid digestion and improve nutrient absorption.

Lactase: Used to break down lactose in dairy products, aiding lactose-intolerant individuals.
Amylase: Facilitates starch digestion in food supplements, improving carbohydrate metabolism.
Protease: Helps with protein breakdown in dietary supplements to enhance digestion and nutrient uptake.

Diagnostic Enzyme

Diagnostic enzymes are essential in clinical testing and laboratory diagnostics.

Glucose oxidase: Used in blood glucose monitoring systems for diabetes management.
Horseradish peroxidase (HRP): Commonly applied in ELISA assays for detecting biomolecules.
Alkaline phosphatase: Utilized in various diagnostic assays to detect abnormal enzyme activity.

Enzyme Development in Mammary Gland Bioreactors

The utilization of mammary gland bioreactors presents a distinctive platform for the efficient, scalable, and cost-effective production of enzymes that surpasses conventional methods in terms of performance. By harnessing the inherent functionality of mammary glands, these bioreactors facilitate the generation of superior recombinant enzymes crucial for diverse applications.

Protein	Transgene Source	Mammary Gland Bioreactor Model	Promoter	Expression Levels
Antithrombin III	Not determined	Transgenic Goat	Goat β casein	14 mg/mL
β-S1-antitrypsin	Not determined	Transgenic Goat	Goat β casein	20 mg/mL
Superoxide dismutase	cDNA	Transgenic Rabbit	Murine WAP	2.9 mg/mL
α1-antitrypsin	Minigene	Transgenic Sheep	Ovine β-lactoglobulin	35 mg/mL

At CD BioSciences, we specialize in leveraging mammary gland bioreactor technology to provide customized enzyme production services of the highest quality. Whether you require therapeutic, industrial, nutritional, or diagnostic enzymes, CD BioSciences is your trusted partner for tailored enzyme production solutions that meet your specific needs. Feel free to contact us for a collaborative exploration of your next groundbreaking endeavor.

Our services are for research use only and cannot be used for any clinical purposes.